n.内分泌物
Leptin is one endogenous excitatory autacoid, encoded by obese gene and secreted by adipose cells. 瘦素(leptin)是肥胖基因(ob基因)编码，脂肪细胞分泌的一种内源性激素，主要调控体重和脂肪分布。
Pathological change is chronic and continual advancement,patients can emerge renal inadequacy,uraemia.excitatory autacoid and cytotoxic drug have bad curative effect and major adverse reaction. 病变呈慢性的进行性发展，可逐渐出现肾功能不全、尿毒症。激素、细胞毒类药物疗效欠佳，且有较大的不良反应。
For the past few years,combined treatment of traditional Chinese medicine and Western medicine is better,and can decrease effectually adverse reaction of excitatory autacoid and immunodepressant. 近年来临床多采用中西医结合治疗膜性肾病，取得了较好的效果，且能有效减少激素及免疫抑制剂的不良反应。
METHODS According to the POF diagnosis standard,the B ultrasound medical equipment to determine ovary size and the blood examination to detect the level of sex excitatory autacoid. 方法按照POF的诊断标准结合问卷调查并对所有样本人群进行一般健康状况了解、B超测定卵巢大小和血液性激素水平检测。
(physiology) of or relating to an autacoid. （生理学）属于或关于自体有效物质（一种作用于体内一定部位的内分泌物,如激素、抑素等）。
