反新陈代谢规律的
fluorouracil (5-FU) is a kind of antimetabolic drug used in clinic. 5-FU has inhibition effect on many kinds of cancer, but it also seriously hurts the normal cells while it kills the cancer cells. 摘要5-氟尿嘧啶(5-FU)是临床上一种抗瘤谱广、有效率高的抗代谢药物。它对多种肿瘤有抑制作用,缺陷是服药有效剂量与中毒量相近,在杀死癌细胞的同时对正常细胞的损伤也较严重。