半胱天冬酶
Caspase family is highly similar to the protein CED of Caenorhabditis elegans on gene sequence and protein structure. Caspase是与秀丽隐杆线虫死亡蛋白CED在基因序列和蛋白质结构上高度同源的一个蛋白家族，该家族蛋白是细胞凋亡执行的重要分子，直接参与凋亡启动、凋亡信号传递及凋亡效应过程。
Objective To investigate the expression of Caspase 3 in the hippocampus of acutely pentylenetetrazole-kindled rats. 目的 研究 Caspase- 3在戊四氮 (pentylenetetrazole,PTZ)急性点燃大鼠海马组织中的表达情况。
The serum alanine transferase (ALT), hepatic Fas mRNA, caspase 3 activity and hepatocyte apoptosis were analyzed. 测定各组的血清谷丙转氨酶 (ALT)、肝组织Fas mRNA表达、caspase 3活性和肝细胞凋亡。
Furthore, Bax translocation, cytochrome c release, and caspase 9 activation wereblocked by Z-VAD. Bax的膜转移、细胞色素C的释放以及Caspase 8
It is a protective mechanism of NGF by inhibiting the caspase cascade reaction induced by caspase-12. 抑制caspase-12介导的caspase级联反应性凋亡途径的激活是NGF减少缺血/再灌注损伤细胞凋亡的机制之一。
