超变量
E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies. 包括高变区的E2蛋白含有中和性抗原表位，能诱导机体产生中和性抗体。
Objective To clarify the significance of antibodies to hypervariable region 1(HVR 1) of hepatitis C virus (HCV) in chronic HCV-infected patients. 目的 探讨慢性丙型肝炎病毒 (HCV)感染者血清中抗高变区 1 (HVR1 )抗体的多型性及其临床意义。
Aim To study the sequence diversity of the hypervariable region 1(HVR1) in the putative envelope protein E2/NS1 of genotype III/2a HCV in Chinese patients. 目的研究中国丙型肝炎患者III/2a型丙型肝炎病毒(HCV)包膜蛋白E2/NS1高变区1(HVR1)序列变异的规律及意义。
The extremely high variability of HCV especially at the hypervariable region of its envelope protein draws back the research to develop a vaccine against it in the traditional ways. 由于HCV具有不同的基因型，基因突变率高，尤其是包膜蛋白中的高变区，使得传统的疫苗制备方法在HCV面前显得束手无策。
The invention discloses a hypervariable region 1 antigen in hepatitis C virus (HCV), and also discloses the purpose of the antigen in the preparation of hepatitis C virus detection reagent. 本发明公开了本发明提供丙型肝炎病毒(HCV)第一高变区抗原，还公开了该抗原在制备丙型肝炎病毒检测试剂中的用途。
