伤害感受器
Then the glia discharge a bevy of chemicals that prod nociceptor terminals to release neurotransmitters in the cord, thus perpetuating a pain signal. 神经胶细胞释出的物质,包括生长因子和称为细胞素的多种分子,还会让背角神经元变得过度活化;
There the nociceptor releases signaling molecules called neurotransmitters that activate neurons in the dorsal horn, prompting them to transmit the alarm message up to the brain. 在此,痛觉受器的神经末梢会释放称为神经传递物的传讯分子,活化背角的神经元,促使它们将警报上传至脑部。
Alternatives to opiates are available as well.Medicines that interfere with calcium channels can prevent the release of neurotransmitters from nociceptor endings in the spinal cord. 鸦片类的替代药物,也是有的:可干扰钙离子通道的药物,也就能阻断痛觉受器的脊髓端释放神经传递物。
Keywords Nociceptor;Capsaicin;Vanilloid receptor;Dorsal root ganglion;Pain; 关键词伤害性感受器;辣椒素;辣椒素受体;背根神经节;疼痛;
Keywords vesicle-associated protein;nociceptor;dorsal root ganglion;dorsal spinal cord;peripheral nerve injury;gene expression regulation;SNARE core complex; 囊泡转运释放相关蛋白;背根神经节;脊髓背角;外周神经损伤;基因表达调控;伤害性感受器;SNARE复合物;